The Role of Free Tissue Transfer in Merkel Cell Carcinoma of the Head and Neck

Merkel cell carcinoma (MCC) is an uncommon neuroendocrine malignancy with a propensity for the head and neck. It typically presents asymptomatically in elderly Caucasians and is characterized by early local and regional spread. There is currently limited data on the appropriate algorithm for treatme...

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Main Authors: Aldo V. Londino III, Brett A. Miles
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Skin Cancer
Online Access:http://dx.doi.org/10.1155/2012/742303
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spelling doaj-6b1207db3de14659a47548b3f8f639e32020-11-24T20:52:58ZengHindawi LimitedJournal of Skin Cancer2090-29052090-29132012-01-01201210.1155/2012/742303742303The Role of Free Tissue Transfer in Merkel Cell Carcinoma of the Head and NeckAldo V. Londino III0Brett A. Miles1Department of Otolaryngology, The Mount Sinai Hospital, New York, NY 10029, USADepartment of Otolaryngology, The Mount Sinai Hospital, New York, NY 10029, USAMerkel cell carcinoma (MCC) is an uncommon neuroendocrine malignancy with a propensity for the head and neck. It typically presents asymptomatically in elderly Caucasians and is characterized by early local and regional spread. There is currently limited data on the appropriate algorithm for treatment of MCC. However, multimodal therapy with wide surgical excision with or without radiation therapy has become standard of care. The location of the primary tumor and intensive adjuvant therapy is often required, provides a challenge to the reconstructive head and neck surgeon. Occasionally, free tissue transfer reconstructive techniques are employed in the reconstruction of MCC defects. This paper will discuss the role of free tissue transfer as a reconstructive option after surgery for advanced head and neck MCC.http://dx.doi.org/10.1155/2012/742303
collection DOAJ
language English
format Article
sources DOAJ
author Aldo V. Londino III
Brett A. Miles
spellingShingle Aldo V. Londino III
Brett A. Miles
The Role of Free Tissue Transfer in Merkel Cell Carcinoma of the Head and Neck
Journal of Skin Cancer
author_facet Aldo V. Londino III
Brett A. Miles
author_sort Aldo V. Londino III
title The Role of Free Tissue Transfer in Merkel Cell Carcinoma of the Head and Neck
title_short The Role of Free Tissue Transfer in Merkel Cell Carcinoma of the Head and Neck
title_full The Role of Free Tissue Transfer in Merkel Cell Carcinoma of the Head and Neck
title_fullStr The Role of Free Tissue Transfer in Merkel Cell Carcinoma of the Head and Neck
title_full_unstemmed The Role of Free Tissue Transfer in Merkel Cell Carcinoma of the Head and Neck
title_sort role of free tissue transfer in merkel cell carcinoma of the head and neck
publisher Hindawi Limited
series Journal of Skin Cancer
issn 2090-2905
2090-2913
publishDate 2012-01-01
description Merkel cell carcinoma (MCC) is an uncommon neuroendocrine malignancy with a propensity for the head and neck. It typically presents asymptomatically in elderly Caucasians and is characterized by early local and regional spread. There is currently limited data on the appropriate algorithm for treatment of MCC. However, multimodal therapy with wide surgical excision with or without radiation therapy has become standard of care. The location of the primary tumor and intensive adjuvant therapy is often required, provides a challenge to the reconstructive head and neck surgeon. Occasionally, free tissue transfer reconstructive techniques are employed in the reconstruction of MCC defects. This paper will discuss the role of free tissue transfer as a reconstructive option after surgery for advanced head and neck MCC.
url http://dx.doi.org/10.1155/2012/742303
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