Expression of novel fusion antiviral proteins ricin a chain-pokeweed antiviral proteins (RTA-PAPs) in Escherichia coli and their inhibition of protein synthesis and of hepatitis B virus in vitro

Expression of novel fusion antiviral proteins ricin a chain-pokeweed antiviral proteins (RTA-PAPs) in Escherichia coli and their inhibition of protein synthesis and of hepatitis B virus in vitro

Abstract Background Ricin A chain (RTA) and Pokeweed antiviral proteins (PAPs) are plant-derived N-glycosidase ribosomal-inactivating proteins (RIPs) isolated from Ricinus communis and Phytolacca Americana respectively. This study was to investigate the potential production amenability and sub-toxic...

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Bibliographic Details
Main Authors: Yasser Hassan, Sherry Ogg, Hui Ge
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Biotechnology
Subjects:
Fusion proteins
Ricin
Pokeweed antiviral protein
Hepatitis B virus
Antiviral agent
Ribosome-inactivating proteins
Online Access:http://link.springer.com/article/10.1186/s12896-018-0458-6

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