A chemist and biologist talk to each other about caged neurotransmitters
Caged compounds are small organic molecules that can be photoactivated with brief pulses of light. They are widely used to study a great variety of biological processes by physiologists, cell biologists and neuroscientists. Initially made and invented by biologists in the late 1970s, they are now ma...
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doaj-6b08186d71a94176b495a06ae1eca59f2021-02-02T08:46:31ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972013-01-0191647310.3762/bjoc.9.81860-5397-9-8A chemist and biologist talk to each other about caged neurotransmittersGraham C.R. Ellis-Davies0Department of Neuroscience, Mount Sinai School of Medicine, One Gustave Levy Place, New York, NY 10029, USACaged compounds are small organic molecules that can be photoactivated with brief pulses of light. They are widely used to study a great variety of biological processes by physiologists, cell biologists and neuroscientists. Initially made and invented by biologists in the late 1970s, they are now made mostly by chemists, often without any dialogue with the end users, the biologists. The idea for this review is to stimulate interaction between the two communities to further the creative development and application of these powerful optical probes.https://doi.org/10.3762/bjoc.9.8caged compoundscell signalingelectrophysiologyneuronal currentsphotolabile neurotransmittersrates of reactionreceptor antagonism |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Graham C.R. Ellis-Davies |
spellingShingle |
Graham C.R. Ellis-Davies A chemist and biologist talk to each other about caged neurotransmitters Beilstein Journal of Organic Chemistry caged compounds cell signaling electrophysiology neuronal currents photolabile neurotransmitters rates of reaction receptor antagonism |
author_facet |
Graham C.R. Ellis-Davies |
author_sort |
Graham C.R. Ellis-Davies |
title |
A chemist and biologist talk to each other about caged neurotransmitters |
title_short |
A chemist and biologist talk to each other about caged neurotransmitters |
title_full |
A chemist and biologist talk to each other about caged neurotransmitters |
title_fullStr |
A chemist and biologist talk to each other about caged neurotransmitters |
title_full_unstemmed |
A chemist and biologist talk to each other about caged neurotransmitters |
title_sort |
chemist and biologist talk to each other about caged neurotransmitters |
publisher |
Beilstein-Institut |
series |
Beilstein Journal of Organic Chemistry |
issn |
1860-5397 |
publishDate |
2013-01-01 |
description |
Caged compounds are small organic molecules that can be photoactivated with brief pulses of light. They are widely used to study a great variety of biological processes by physiologists, cell biologists and neuroscientists. Initially made and invented by biologists in the late 1970s, they are now made mostly by chemists, often without any dialogue with the end users, the biologists. The idea for this review is to stimulate interaction between the two communities to further the creative development and application of these powerful optical probes. |
topic |
caged compounds cell signaling electrophysiology neuronal currents photolabile neurotransmitters rates of reaction receptor antagonism |
url |
https://doi.org/10.3762/bjoc.9.8 |
work_keys_str_mv |
AT grahamcrellisdavies achemistandbiologisttalktoeachotheraboutcagedneurotransmitters AT grahamcrellisdavies chemistandbiologisttalktoeachotheraboutcagedneurotransmitters |
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