IRAK-M regulation and function in host defense and immune homeostasis

IRAK-M regulation and function in host defense and immune homeostasis

Antigen presenting cells (APCs) of the innate immune system sense a wide range of pathogens via pattern recognition receptors (PRRs). Engagement of certain PRRs can induce production of pro-inflammatory mediators that facilitate effective clearance of pathogen. Toll-like receptors (TLRs) are a well...

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Bibliographic Details
Main Authors: Leah L.N. Hubbard, Bethany B. Moore
Format: Article
Language:English
Published: MDPI AG 2010-06-01
Series:Infectious Disease Reports
Subjects:
sepsis, immune regulation, inflammation
Online Access:http://www.pagepress.org/journals/index.php/idr/article/view/1850

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