LncRNA SPANXA2-OT1 Participates in the Occurrence and Development of EMT in Calcium Oxalate Crystal-Induced Kidney Injury by Adsorbing miR-204 and Up-Regulating Smad5

LncRNA SPANXA2-OT1 Participates in the Occurrence and Development of EMT in Calcium Oxalate Crystal-Induced Kidney Injury by Adsorbing miR-204 and Up-Regulating Smad5

Objective: To explore the regulatory mechanism of long non-coding RNAs (lncRNAs) in the occurrence and development of epithelial-mesenchymal transition (EMT) in calcium oxalate crystal-induced kidney injury.Materials and Methods: Gene core technique was used to screen differentially expressed lncRNA...

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Bibliographic Details
Main Authors: Haiyan Hu, Jie Zhang, Yinhui Li, Jiarong Ding, Wei Chen, Zhiyong Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Medicine
Subjects:
crystalline kidney injury
epithelial-mesenchymal trans-differentiation
lncRNA SPANXA2-OT1
miR-204
Smad5
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.719980/full

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