Methylation as a key regulator of Tau aggregation and neuronal health in Alzheimer’s disease

Abstract Neurodegenerative diseases like Alzheimer’s, Parkinson’s and Huntington’s disease involves abnormal aggregation and accumulation of toxic proteins aggregates. Post-translational modifications (PTMs) of the causative proteins play an important role in the etiology of disease as they could ei...

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Bibliographic Details
Main Authors: Abhishek Ankur Balmik, Subashchandrabose Chinnathambi
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Cell Communication and Signaling
Subjects:
Tau
Online Access:https://doi.org/10.1186/s12964-021-00732-z