Quantitative kinetic study of the actin-bundling protein L-plastin and of its impact on actin turn-over.

Quantitative kinetic study of the actin-bundling protein L-plastin and of its impact on actin turn-over.

BACKGROUND: Initially detected in leukocytes and cancer cells derived from solid tissues, L-plastin/fimbrin belongs to a large family of actin crosslinkers and is considered as a marker for many cancers. Phosphorylation of L-plastin on residue Ser5 increases its F-actin binding activity and is requi...

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Main Authors: Ziad Al Tanoury, Elisabeth Schaffner-Reckinger, Aliaksandr Halavatyi, Céline Hoffmann, Michèle Moes, Ermin Hadzic, Marie Catillon, Mikalai Yatskou, Evelyne Friederich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2821400?pdf=render

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