Effect of β-Hydroxybutyrate on Autophagy Dynamics During Severe Hypoglycemia and the Hypoglycemic Coma

Effect of β-Hydroxybutyrate on Autophagy Dynamics During Severe Hypoglycemia and the Hypoglycemic Coma

Glucose supply from blood is mandatory for brain functioning and its interruption during acute hypoglycemia or cerebral ischemia leads to brain injury. Alternative substrates to glucose such as the ketone bodies (KB), acetoacetate (AcAc), and β-hydroxybutyrate (BHB), can be used as energy fuels in t...

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Bibliographic Details
Main Authors: Carmen Torres-Esquivel, Teresa Montiel, Marco Flores-Méndez, Lourdes Massieu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
hypoglycemia
ketone bodies
neuronal death
autophagy
AMPK
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.547215/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.547215/full

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