Comprehensive Analysis of Disease-Related Genes in Chronic Lymphocytic Leukemia by Multiplex PCR-Based Next Generation Sequencing.

Comprehensive Analysis of Disease-Related Genes in Chronic Lymphocytic Leukemia by Multiplex PCR-Based Next Generation Sequencing.

High resolution molecular studies have demonstrated that the clonal acquisition of gene mutations is an important mechanism that may promote rapid disease progression and drug resistance in chronic lymphocytic leukemia (CLL). Therefore, the early and sensitive detection of such mutations is an impor...

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Bibliographic Details
Main Authors: Claudia Vollbrecht, Fabian Dominik Mairinger, Ulrike Koitzsch, Martin Peifer, Katharina Koenig, Lukas Carl Heukamp, Giuliano Crispatzu, Laura Wilden, Karl-Anton Kreuzer, Michael Hallek, Margarete Odenthal, Carmen Diana Herling, Reinhard Buettner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4459702?pdf=render

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http://europepmc.org/articles/PMC4459702?pdf=render

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