Comparative Genomic Analysis of Two Clonally Related Multidrug Resistant Mycobacterium tuberculosis by Single Molecule Real Time Sequencing

Comparative Genomic Analysis of Two Clonally Related Multidrug Resistant Mycobacterium tuberculosis by Single Molecule Real Time Sequencing

Background: Multidrug-resistant tuberculosis (MDR-TB) is posing a major threat to global TB control. In this study, we focused on two consecutive MDR-TB isolated from the same patient before and after the initiation of anti-TB treatment. To better understand the genomic characteristics of MDR-TB, Si...

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Bibliographic Details
Main Authors: Kenneth Siu-Sing Leung, Gilman Kit-Hang Siu, Kingsley King-Gee Tam, Sabrina Wai-Chi To, Rahim Rajwani, Pak-Leung Ho, Samson Sai-Yin Wong, Wei W. Zhao, Oliver Chiu-Kit Ma, Wing-Cheong Yam
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
multidrug resistance
Mycobacterium tuberculosis
PacBio sequencing
growth rate
comparative genomic analysis
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00478/full

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http://journal.frontiersin.org/article/10.3389/fcimb.2017.00478/full

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