Importance of bone marrow biopsy in assessment of treatment response in a case of acute myeloid leukemia
Chemotherapy response in acute leukemias is usually assessed by bone marrow examination along with ancillary studies like flowcytometry/ polymerase chain reaction for minimal residual disease (MRD). Decisions regarding post induction chemotherapy are based on bone marrow remission status. Bone marro...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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KIMS Foundation and Research Center
2020-10-01
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| Series: | Journal of Medical and Scientific Research |
| Subjects: | |
| Online Access: | http://jmsronline.com/article.aspx?ID=bone-marrow-biopsy-assessment-treatment-response-acute%20myeloid-leukemia |
| Summary: | Chemotherapy response in acute leukemias is usually assessed by bone marrow examination along with ancillary studies like flowcytometry/ polymerase chain reaction for minimal residual disease (MRD). Decisions regarding post induction chemotherapy are based on bone marrow remission status. Bone marrow aspiration alone is asked by many oncologists/ hematologists for assessing the remission status. Rarely pockets/ clusters of blasts may not be picked up in the aspiration and the same for MRD also. Hence, bone marrow biopsy is necessary for those clusters/ pockets of blasts. In this case report we are highlighting the importance of both aspiration and biopsy for assessing the treatment response. |
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| ISSN: | 2321-1326 2394-112X |