Lactobacillus gasseri SBT2055 induces TGF-β expression in dendritic cells and activates TLR2 signal to produce IgA in the small intestine.

Lactobacillus gasseri SBT2055 induces TGF-β expression in dendritic cells and activates TLR2 signal to produce IgA in the small intestine.

Probiotic bacteria provide benefits in enhancing host immune responses and protecting against infection. Induction of IgA production by oral administration of probiotic bacteria in the intestine has been considered to be one reason for this beneficial effect, but the mechanisms of the effect are poo...

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Bibliographic Details
Main Authors: Fumihiko Sakai, Tomohiro Hosoya, Aiko Ono-Ohmachi, Ken Ukibe, Akihiro Ogawa, Tomohiro Moriya, Yukio Kadooka, Takuya Shiozaki, Hisako Nakagawa, Yosuke Nakayama, Tadaaki Miyazaki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4140756?pdf=render

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