Familial Adenomatous Polyposis—Rendering a Diagnosis Based on Recognition of an Unusual Primary Thyroid Neoplasm

Familial Adenomatous Polyposis—Rendering a Diagnosis Based on Recognition of an Unusual Primary Thyroid Neoplasm

It has been well established in the literature that the cribriform-morular variant of papillary thyroid carcinoma (CMVPTC) has been observed with higher frequency in familial adenomatous polyposis (FAP) patients. In the usual setting, patients with FAP are identified based on their germline mutation...

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Main Authors: David F. Schaeffer, Eric M. Yoshida, David A. Owen, Kenneth W. Berean
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2011/767610
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spelling doaj-6a800c9d38fc416488052205dc271b5f2020-11-25T00:48:56ZengHindawi LimitedCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/767610767610Familial Adenomatous Polyposis—Rendering a Diagnosis Based on Recognition of an Unusual Primary Thyroid NeoplasmDavid F. Schaeffer0Eric M. Yoshida1David A. Owen2Kenneth W. Berean3Department of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, BC, V6T 1Z4, CanadaDepartment of Medicine, The University of British Columbia, Vancouver, BC, V6T 1Z4, CanadaDepartment of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, BC, V6T 1Z4, CanadaDepartment of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, BC, V6T 1Z4, CanadaIt has been well established in the literature that the cribriform-morular variant of papillary thyroid carcinoma (CMVPTC) has been observed with higher frequency in familial adenomatous polyposis (FAP) patients. In the usual setting, patients with FAP are identified based on their germline mutations and the diagnosis of thyroid neoplasm is made after the FAP diagnosis. We herein report a case in which the recognition of a CMVPTC led to the initial diagnosis of FAP. The histological and clinical features of CMVPTC are reviewed with emphasis on its relationship to FAP.http://dx.doi.org/10.1155/2011/767610
collection DOAJ
language English
format Article
sources DOAJ
author David F. Schaeffer
Eric M. Yoshida
David A. Owen
Kenneth W. Berean
spellingShingle David F. Schaeffer
Eric M. Yoshida
David A. Owen
Kenneth W. Berean
Familial Adenomatous Polyposis—Rendering a Diagnosis Based on Recognition of an Unusual Primary Thyroid Neoplasm
Case Reports in Medicine
author_facet David F. Schaeffer
Eric M. Yoshida
David A. Owen
Kenneth W. Berean
author_sort David F. Schaeffer
title Familial Adenomatous Polyposis—Rendering a Diagnosis Based on Recognition of an Unusual Primary Thyroid Neoplasm
title_short Familial Adenomatous Polyposis—Rendering a Diagnosis Based on Recognition of an Unusual Primary Thyroid Neoplasm
title_full Familial Adenomatous Polyposis—Rendering a Diagnosis Based on Recognition of an Unusual Primary Thyroid Neoplasm
title_fullStr Familial Adenomatous Polyposis—Rendering a Diagnosis Based on Recognition of an Unusual Primary Thyroid Neoplasm
title_full_unstemmed Familial Adenomatous Polyposis—Rendering a Diagnosis Based on Recognition of an Unusual Primary Thyroid Neoplasm
title_sort familial adenomatous polyposis—rendering a diagnosis based on recognition of an unusual primary thyroid neoplasm
publisher Hindawi Limited
series Case Reports in Medicine
issn 1687-9627
1687-9635
publishDate 2011-01-01
description It has been well established in the literature that the cribriform-morular variant of papillary thyroid carcinoma (CMVPTC) has been observed with higher frequency in familial adenomatous polyposis (FAP) patients. In the usual setting, patients with FAP are identified based on their germline mutations and the diagnosis of thyroid neoplasm is made after the FAP diagnosis. We herein report a case in which the recognition of a CMVPTC led to the initial diagnosis of FAP. The histological and clinical features of CMVPTC are reviewed with emphasis on its relationship to FAP.
url http://dx.doi.org/10.1155/2011/767610
work_keys_str_mv AT davidfschaeffer familialadenomatouspolyposisrenderingadiagnosisbasedonrecognitionofanunusualprimarythyroidneoplasm
AT ericmyoshida familialadenomatouspolyposisrenderingadiagnosisbasedonrecognitionofanunusualprimarythyroidneoplasm
AT davidaowen familialadenomatouspolyposisrenderingadiagnosisbasedonrecognitionofanunusualprimarythyroidneoplasm
AT kennethwberean familialadenomatouspolyposisrenderingadiagnosisbasedonrecognitionofanunusualprimarythyroidneoplasm
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