Integrative genomic analysis of blood pressure and related phenotypes in rats

Integrative genomic analysis of blood pressure and related phenotypes in rats

Despite remarkable progress made in human genome-wide association studies, there remains a substantial gap between statistical evidence for genetic associations and functional comprehension of the underlying mechanisms governing these associations. As a means of bridging this gap, we performed genom...

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Bibliographic Details
Main Authors: Fumihiko Takeuchi, Yi-Qiang Liang, Masato Isono, Michiko Tajima, Zong Hu Cui, Yoko Iizuka, Takanari Gotoda, Toru Nabika, Norihiro Kato
Format: Article
Language:English
Published: The Company of Biologists 2021-05-01
Series:Disease Models & Mechanisms
Subjects:
gene
locus
transcriptome
blood pressure
multifactorial disease
genome-wide association studies
Online Access:http://dmm.biologists.org/content/14/5/dmm048090

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