Systematic Review and Network Meta-Analysis: Comparative Efficacy and Safety of Biosimilars, Biologics and JAK1 Inhibitors for Active Crohn Disease

Systematic Review and Network Meta-Analysis: Comparative Efficacy and Safety of Biosimilars, Biologics and JAK1 Inhibitors for Active Crohn Disease

Background: Crohn disease (CD) is a chronic inflammatory disease that affects quality of life. There are several drugs available for the treatment of CD, but their relative efficacy is unknown due to a lack of high-quality head-to-head randomized controlled trials.Aim: To perform a mixed comparison...

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Bibliographic Details
Main Authors: Guozhi Wu, Yuan Yang, Min Liu, Yuping Wang, Qinghong Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
biosimilar
biologics
JAK inhibitors
Crohn disease
network meta analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.655865/full

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