Regulation of Rho Family GTPases by Cell-Cell and Cell-Matrix Adhesion

Integrins and cadherins are transmembrane adhesion receptors that are necessary for cells to interact with the extracellular matrix or adjacent cells, respectively. Integrins and cadherins initiate signaling pathways that modulate the activity of Rho family GTPases. The Rho proteins Cdc42, Rac1, and...

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Bibliographic Details
Main Authors: WILLIAM T. ARTHUR, NICOLE K. NOREN, KEITH BURRIDGE
Format: Article
Language:English
Published: BMC 2002-01-01
Series:Biological Research
Subjects:
Rho
Rac
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000200016