B-cell acute lymphoblastic leukemia with t(4;11)(q21;q23) in a young woman: evolution into mixed phenotype acute leukemia with additional chromosomal aberrations in the course of therapy

B-cell acute lymphoblastic leukemia with t(4;11)(q21;q23) in a young woman: evolution into mixed phenotype acute leukemia with additional chromosomal aberrations in the course of therapy

About 5% of adult B-cell acute lymphoblastic leukemias (B-ALL) are characterized by t(4;11)(q21;q23), which confers peculiar features to this B-ALL subtype, including a very immature immunophenotype and poor prognosis. We describe the case of a 21-year-old female who presented with B-ALL carrying th...

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Bibliographic Details
Main Authors: Giovanni Carulli, Alessandra Marini, Maria I. Ferreri, Antonio Azzarà, Virginia Ottaviano, Tiziana Lari, Melania Rocco, Stefano Giuntini, Mario Petrini
Format: Article
Language:English
Published: PAGEPress Publications 2012-09-01
Series:Hematology Reports
Subjects:
acute lymphoblastic leukemia
acute myeloid leukemia
mixed phenotype acute leukemia
MLL gene
t(4
11)(q21
q23)
Online Access:http://www.pagepress.org/journals/index.php/hr/article/view/4190

Internet

http://www.pagepress.org/journals/index.php/hr/article/view/4190

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