Additional New Minor Cucurbitane Glycosides from Siraitia grosvenorii

• Main Authors: Indra Prakash, Venkata Sai Prakash Chaturvedula
• Format: Article
• Language: English
• Published: MDPI AG 2014-03-01
• Series: Molecules
• Subjects: Siraitia grosvenorii; curcubitaceae; Luo Han Guo; curcubitane glycosides; structure elucidation; NMR; MS
• Online Access: http://www.mdpi.com/1420-3049/19/3/3669
• ISSN: 1420-3049

Continuous phytochemical studies of the crude extract of Luo Han Guo (Siraitia grosvenorii) furnished three additional new cucurbitane triterpene glycosides, namely 11-deoxymogroside V, 11-deoxyisomogroside V, and 11-deoxymogroside VI. The structures of all the isolated compounds were characterized on the basis of extensive NMR and mass spectral data as well as hydrolysis studies. The complete 1H- and 13C-NMR spectral assignments of the three unknown compounds are reported for the first time based on COSY, TOCSY, HSQC, and HMBC spectroscopic data.