Association between local immune cell infiltration, mismatch repair status and systemic inflammatory response in colorectal cancer

Association between local immune cell infiltration, mismatch repair status and systemic inflammatory response in colorectal cancer

Abstract Background Systemic inflammatory response in colorectal cancer (CRC) has been established as a prognostic factor for impaired cancer-specific survival, predominantly in patients with right-sided tumors. On the other hand, defective mismatch repair (dMMR) tumors, primarily located in the rig...

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Bibliographic Details
Main Authors: Ulf Gunnarsson, Karin Strigård, Sofia Edin, Ioannis Gkekas, Harri Mustonen, Tuomas Kaprio, Camilla Böckelman, Jaana Hagström, Richard Palmqvist, Caj Haglund
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Translational Medicine
Subjects:
Colorectal cancer
Local immune response
Systematic inflammatory response
Miscrosatellite instability
Mismatch repair
Online Access:http://link.springer.com/article/10.1186/s12967-020-02336-6

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