CD26/DPP-4: Type 2 Diabetes Drug Target with Potential Influence on Cancer Biology

DPP-4/CD26, a membrane-bound glycoprotein, is ubiquitously expressed and has diverse biological functions. Because of its enzymatic action, such as the degradation of incretin hormones, DPP-4/CD26 is recognized as the significant therapeutic target for type 2 diabetes (T2DM); DPP-4 inhibitors have b...

Full description

Bibliographic Details
Main Authors: Emi Kawakita, Daisuke Koya, Keizo Kanasaki
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/9/2191