A hidden Markov tree model for testing multiple hypotheses corresponding to Gene Ontology gene sets
Abstract Background Testing predefined gene categories has become a common practice for scientists analyzing high throughput transcriptome data. A systematic way of testing gene categories leads to testing hundreds of null hypotheses that correspond to nodes in a directed acyclic graph. The relation...
Main Authors: | Kun Liang, Chuanlong Du, Hankun You, Dan Nettleton |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-03-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-018-2106-5 |
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