A potential role of the JNK pathway in hyperoxia-induced cell death, myofibroblast transdifferentiation and TGF-β1-mediated injury in the developing murine lung

A potential role of the JNK pathway in hyperoxia-induced cell death, myofibroblast transdifferentiation and TGF-β1-mediated injury in the developing murine lung

<p>Abstract</p> <p>Background</p> <p>Transforming growth factor-beta 1 (TGF-β1) has been implicated in hyperoxia-induced cell death and impaired alveolarization in the developing lung. In addition, the c-JunNH2-terminal kinase (JNK) pathway has been shown to have a role...

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Bibliographic Details
Main Authors: Li Zhang, Choo-Wing Rayman, Sun Huanxing, Sureshbabu Angara, Sakurai Reiko, Rehan Virender K, Bhandari Vineet
Format: Article
Language:English
Published: BMC 2011-12-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/12/54

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