Metabolic benefits of novel histamine H3 receptor ligands in the model of excessive eating: The importance of intrinsic activity and pharmacokinetic properties

Metabolic benefits of novel histamine H3 receptor ligands in the model of excessive eating: The importance of intrinsic activity and pharmacokinetic properties

Aims: One of the therapeutic approaches in the treatment of obesity is the use of histamine H3 receptor ligands. Histamine plays a significant role in eating behavior because it causes a loss of appetite and is considered to be a satiety signal released during food intake. Material and methods: Hist...

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Bibliographic Details
Main Authors: Kamil Mika, Małgorzata Szafarz, Marek Bednarski, Kamil Kuder, Katarzyna Szczepańska, Krzysztof Pociecha, Bartosz Pomierny, Katarzyna Kieć-Kononowicz, Jacek Sapa, Magdalena Kotańska
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Histamine H3 receptor ligands
Model of excessive eating
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221007344

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