Parkinson's disease genetic risk in a midbrain neuronal cell line

In genome-wide association studies of complex diseases, many risk polymorphisms are found to lie in non-coding DNA and likely confer risk through allele-dependent differences in gene regulatory elements. However, because distal regulatory elements can alter gene expression at various distances on li...

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Bibliographic Details
Main Authors: Steven E. Pierce, Trevor Tyson, Alix Booms, Jordan Prahl, Gerhard A. Coetzee
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118300391