Half-Barrels Derived from a (β/α)8 Barrel β-Glycosidase Undergo an Activation Process.

The evolution of (β/α)8 barrel proteins is currently thought to have involved the fusion of two (β/α)4 half-barrels, thereby conferring stability on the protein structure. After the formation of a whole (β/α)8 barrel, this structure could evolve and diverge to form fully active enzymes. Interestingl...

Full description

Bibliographic Details
Main Authors: Daniela Beton, Sandro R Marana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4591997?pdf=render