Four New Citrinin Derivatives from a Marine-Derived Penicillium sp. Fungal Strain

Four new citrinin derivatives, including two citrinin dimers and two citrinin monomer derivatives, were isolated and identified from a marine-derived fungal strain Penicillium sp. ML226 along with six known related compounds. Their structures were elucidated by spectroscopic and chemical methods. Th...

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Bibliographic Details
Main Authors: Zhong Hui Zheng, Si Yang Song, Qing Yan Xu, Zhi Yu Hu, Chun Hua Lu, Mei Ling Wang
Format: Article
Language:English
Published: MDPI AG 2013-05-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/5/5723
Description
Summary:Four new citrinin derivatives, including two citrinin dimers and two citrinin monomer derivatives, were isolated and identified from a marine-derived fungal strain Penicillium sp. ML226 along with six known related compounds. Their structures were elucidated by spectroscopic and chemical methods. The new compounds showed modest cytotoxic activity against HepG-2 cell line and weak antimicrobial activity against Staphylococcus aureus.
ISSN:1420-3049