Evaluation of Three Morphologically Distinct Virus-Like Particles as Nanocarriers for Convection-Enhanced Drug Delivery to Glioblastoma

Evaluation of Three Morphologically Distinct Virus-Like Particles as Nanocarriers for Convection-Enhanced Drug Delivery to Glioblastoma

Glioblastoma is a particularly challenging cancer, as there are currently limited options for treatment. New delivery routes are being explored, including direct intratumoral injection via convection-enhanced delivery (CED). While promising, convection-enhanced delivery of traditional chemotherapeut...

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Bibliographic Details
Main Authors: Joel A. Finbloom, Ioana L. Aanei, Jenna M. Bernard, Sarah H. Klass, Susanna K. Elledge, Kenneth Han, Tomoko Ozawa, Theodore P. Nicolaides, Mitchel S. Berger, Matthew B. Francis
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Nanomaterials
Subjects:
virus-like particles
glioblastoma
convection-enhanced delivery
tobacco mosaic virus
bioconjugation
doxorubicin
drug delivery
protein-based nanomaterials
viral capsid
Online Access:https://www.mdpi.com/2079-4991/8/12/1007

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