Effect of milrinone on the inflammatory response and NF-kB activation in renal ischemia-reperfusion injury in mice

Effect of milrinone on the inflammatory response and NF-kB activation in renal ischemia-reperfusion injury in mice

BackgroundMilrinone increases intracellular adenosine 3',5'-cyclic monophosphate concentration and enhances vascular relaxation. Nuclear factor-kappa B (NF-kB) plays a key role in inflammatory responses during ischemia-reperfusion (I/R) injury. We aimed to investigate the effect of milrino...

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Bibliographic Details
Main Authors: Hong Soo Jung, Jin-Deok Joo, Dae-Woo Kim, Jang Hyeok In, Misun Roh, Jong-Tae Jeong, Seung June Noh, Jin Woo Choi
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2014-02-01
Series:Korean Journal of Anesthesiology
Subjects:
ischemia-reperfusion injury
milrinone
nuclear-factor-kappa b
Online Access:http://ekja.org/upload/pdf/kjae-66-136.pdf

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