Differential requirement of cyclin-dependent kinase 2 for oligodendrocyte progenitor cell proliferation and differentiation

Differential requirement of cyclin-dependent kinase 2 for oligodendrocyte progenitor cell proliferation and differentiation

<p>Abstract</p> <p>Cyclin-dependent kinases (Cdks) and their cyclin regulatory subunits control cell growth and division. Cdk2-cyclin E complexes, phosphorylating the retinoblastoma protein, drive cells through the G1/S transition into the S phase of the cell cycle. Despite its fun...

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Bibliographic Details
Main Authors: Caillava Céline, Baron-Van Evercooren Anne
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Cell Division
Subjects:
Cdk2
Proliferation
Remyelination
Oligodendrocyte progenitor
Adult neural stem cell
Online Access:http://www.celldiv.com/content/7/1/14

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