The Ca2+ Channel Iinhibitor NNC 55-0396 Inhibits Voltage-Dependent K+ Channels in Rabbit Coronary Arterial Smooth Muscle Cells

The Ca2+ Channel Iinhibitor NNC 55-0396 Inhibits Voltage-Dependent K+ Channels in Rabbit Coronary Arterial Smooth Muscle Cells

Abstract.: We demonstrated the inhibitory effect of NNC 55-0396, a T-type Ca2+ channel inhibitor, on voltage-dependent K+ (KV) channels in freshly isolated rabbit coronary arterial smooth muscle cells. NNC 55-0396 decreased the amplitude of KV currents in a concentration-dependent manner, with an IC...

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Bibliographic Details
Main Authors: Youn Kyoung Son, Da Hye Hong, Hongliang Li, Dae-Joong Kim, Sung Hun Na, Hongzoo Park, Won-Kyo Jung, Il-Whan Choi, Won Sun Park
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319301252

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http://www.sciencedirect.com/science/article/pii/S1347861319301252

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