Fluorescent Protein-Tagged Sindbis Virus E2 Glycoprotein Allows Single Particle Analysis of Virus Budding from Live Cells

Fluorescent Protein-Tagged Sindbis Virus E2 Glycoprotein Allows Single Particle Analysis of Virus Budding from Live Cells

Sindbis virus (SINV) is an enveloped, mosquito-borne alphavirus. Here we generated and characterized a fluorescent protein-tagged (FP-tagged) SINV and found that the presence of the FP-tag (mCherry) affected glycoprotein transport to the plasma membrane whereas the specific infectivity of the virus...

Full description

Bibliographic Details
Main Authors: Joyce Jose, Jinghua Tang, Aaron B. Taylor, Timothy S. Baker, Richard J. Kuhn
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Viruses
Subjects:
alphavirus
live imaging
virus assembly
filopodia
virus egress
Online Access:http://www.mdpi.com/1999-4915/7/12/2926

Similar Items

Similar Items