The Profile of Toll-like Receptor 2 (TLR2), TLR4 and Their Cytosolic Downstream Signaling Pathway in Common Variable Immunodeficiency (CVID) Patients

Common variable immunodeficiency (CVID) is the most common clinical primary antibody deficiency, characterized by increased susceptibility to recurrent bacterial infections. Since Toll-like receptors (TLRs) play an important role in the maturation and differentiation of B-cells, TLRs’ defect can be...

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Bibliographic Details
Main Authors:	Laleh Sharifi, Asghar Aghamohammadi, Nima Rezaei, Reza Yazdani, Mahdi Mahmoudi, Mohammad Mehdi Amiri, Farimah Masoumi, Saied Bokaie, Parsova Tavasolian, Rouzbeh Sanaei, Mona Moshiri, Naeimeh Tavakolinia, Tina Alinia, Gholamreza Azizi, Abbas Mirshafiey
Format:	Article
Language:	English
Published:	Tehran University of Medical Sciences 2018-04-01
Series:	Iranian Journal of Allergy, Asthma and Immunology
Subjects:	Common variable immunodeficiency (CVID) Myeloid differentiation primary response 88 (MyD88) Toll-like receptor 2 (TLR2) Toll-like receptor 4 (TLR4) Toll interacting protein (Tollip)
Online Access:	https://ijaai.tums.ac.ir/index.php/ijaai/article/view/1425

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