Up-regulation of microRNA-200c-3p inhibits invasion and migration of renal cell carcinoma cells via the SOX2-dependent Wnt/β-catenin signaling pathway

Up-regulation of microRNA-200c-3p inhibits invasion and migration of renal cell carcinoma cells via the SOX2-dependent Wnt/β-catenin signaling pathway

Abstract Background MicroRNA-200c-3p (miR-200c-3p) has been revealed to be related to renal cell carcinoma (RCC) progression, while the inner mechanisms remain unknown. In our study, we intend to unearth the capability of miR-200c-3p in RCC development via the Wnt/β-catenin signaling pathway through...

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Bibliographic Details
Main Authors: Shuai Li, Ziyu Feng, Xuechong Zhang, Dongyang Lan, Yudong Wu
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Cancer Cell International
Subjects:
microRNA-200c-3p
Renal cell carcinoma
SOX2
Wnt/β-catenin signaling pathway
Proliferation
Invasion
Online Access:http://link.springer.com/article/10.1186/s12935-019-0944-5

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