Bacterial endotoxins: biological properties and mechanisms of action
Endotoxins (lipopolysaccharides, LPS) are agents of pathogenicity of Gram-negative bacteria, implicated in the development of Gram-negative shock. Endotoxin reacts with lipopolysaccharide-sensitive cells producing endogenous mediators such as tumour necrosis factor alpha (TNFα). Macrophages are cell...
Main Authors: | C. Galanos, M. A. Freudenberg |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
1993-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/S0962935193000687 |
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