Extremophilic 50S Ribosomal RNA-Binding Protein L35Ae as a Basis for Engineering of an Alternative Protein Scaffold.

Extremophilic 50S Ribosomal RNA-Binding Protein L35Ae as a Basis for Engineering of an Alternative Protein Scaffold.

Due to their remarkably high structural stability, proteins from extremophiles are particularly useful in numerous biological applications. Their utility as alternative protein scaffolds could be especially valuable in small antibody mimetic engineering. These artificial binding proteins occupy a sp...

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Bibliographic Details
Main Authors: Anna V Lomonosova, Elena V Ovchinnikova, Alexei S Kazakov, Alexander I Denesyuk, Alexander D Sofin, Roman V Mikhailov, Andrei B Ulitin, Tajib A Mirzabekov, Eugene A Permyakov, Sergei E Permyakov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0134906

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