Hormonal Therapy Resistance and Breast Cancer: Involvement of Adipocytes and Leptin

Hormonal Therapy Resistance and Breast Cancer: Involvement of Adipocytes and Leptin

Obesity, a recognized risk factor for breast cancer in postmenopausal women, is associated with higher mortality rates regardless of menopausal status, which could in part be explained by therapeutic escape. Indeed, adipose microenvironment has been described to influence the efficiency of chemo- an...

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Bibliographic Details
Main Authors: Laetitia Delort, Lauriane Bougaret, Juliette Cholet, Marion Vermerie, Hermine Billard, Caroline Decombat, Céline Bourgne, Marc Berger, Charles Dumontet, Florence Caldefie-Chezet
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Nutrients
Subjects:
breast cancer
adipose secretome
leptin
hormonal therapy resistance
cancer stem cells
Online Access:https://www.mdpi.com/2072-6643/11/12/2839

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