Statistically efficient association analysis of quantitative traits with haplotypes and untyped SNPs in family studies
Abstract Background Associations between haplotypes and quantitative traits provide valuable information about the genetic basis of complex human diseases. Haplotypes also provide an effective way to deal with untyped SNPs. Two major challenges arise in haplotype-based association analysis of family...
Main Authors: | Guoqing Diao, Dan-yu Lin |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2020-09-01
|
Series: | BMC Genetics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12863-020-00902-x |
Similar Items
-
Hardy Weinberg Equilibrium Disturbances in Case-Control Studies Lead to Non-Conclusive Results
by: Jose Luis Royo
Published: (2021-01-01) -
Hardy Weinberg Equilibrium Testing and Interpretation: Focus on infection
by: Sana Eybpoosh
Published: (2018-01-01) -
The Hardy-Weinberg principle
by: Stark Alan E.
Published: (2005-01-01) -
A straightforward multiallelic significance test for the Hardy-Weinberg equilibrium law
by: Marcelo S. Lauretto, et al.
Published: (2009-01-01) -
Prevalence of adenylosuccinate lyase deficiency based on aggregated exome data
by: Carlos R. Ferreira
Published: (2017-03-01)