Peptide Nucleic Acid Knockdown and Intra-host Cell Complementation of Ehrlichia Type IV Secretion System Effector

Peptide Nucleic Acid Knockdown and Intra-host Cell Complementation of Ehrlichia Type IV Secretion System Effector

Survival of Ehrlichia chaffeensis depends on obligatory intracellular infection. One of the barriers to E. chaffeensis research progress has been the inability, using conventional techniques, to generate knock-out mutants for genes essential for intracellular infection. This study examined the use o...

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Bibliographic Details
Main Authors: Pratibha Sharma, Omid Teymournejad, Yasuko Rikihisa
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
PNA
Ehrlichia chaffeensis
type IV secretion
complementation
autophagy
effector
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00228/full

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