Wound Fluid from Breast Cancer Patients Undergoing Intraoperative Radiotherapy Exhibits an Altered Cytokine Profile and Impairs Mesenchymal Stromal Cell Function

Wound Fluid from Breast Cancer Patients Undergoing Intraoperative Radiotherapy Exhibits an Altered Cytokine Profile and Impairs Mesenchymal Stromal Cell Function

Intraoperative radiotherapy (IORT) displays an increasingly used treatment option for early breast cancer. It exhibits non-inferiority concerning the risk of recurrence compared to conventional external irradiation (EBRT) in suitable patients with early breast cancer. Since most relapses occur in di...

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Bibliographic Details
Main Authors: Anne Wuhrer, Stefanie Uhlig, Benjamin Tuschy, Sebastian Berlit, Elena Sperk, Karen Bieback, Marc Sütterlin
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
breast cancer
intraoperative radiotherapy
tumor microenvironment
mesenchymal stromal cells
oncostatin-M
IL-1β
Online Access:https://www.mdpi.com/2072-6694/13/9/2140

Internet

https://www.mdpi.com/2072-6694/13/9/2140

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