The Effect of Metformin on Self-Selected Exercise Intensity in Healthy, Lean Males: A Randomized, Crossover, Counterbalanced Trial

The Effect of Metformin on Self-Selected Exercise Intensity in Healthy, Lean Males: A Randomized, Crossover, Counterbalanced Trial

IntroductionIn general, patients with type 2 diabetes have lower cardiorespiratory fitness levels and perform exercise at lower intensities compared to healthy controls. Since metformin (MET) has been shown to increase the rate of perceived exertion (RPE) during exercise with a fixed intensity, MET...

Full description

Bibliographic Details
Main Authors:	Nanna Skytt Pilmark, Christina Petersen-Bønding, Nielse Frederich Rose Holm, Mette Yun Johansen, Bente Klarlund Pedersen, Katrine Bagge Hansen, Kristian Karstoft
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-02-01
Series:	Frontiers in Endocrinology
Subjects:	exercise metformin rate of perceived exertion type 2 diabetes self-selected exercise intensity
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2021.599164/full

Similar Items

Editorial: Understanding the Heterogeneity in Exercise-Induced Changes in Glucose Metabolism to Help Optimize Treatment Outcomes
by: Thomas P. J. Solomon, et al.
Published: (2021-05-01)

Editorial: Optimizing Exercise for the Prevention and Treatment of Type 2 Diabetes
by: Kristian Karstoft, et al.
Published: (2018-05-01)

The Effect of Diet, Exercise and Metformin on the Progression of Prostate Cancer
by: Ge, Xiangfeng
Published: (2014)

The Effect of Diet, Exercise and Metformin on the Progression of Prostate Cancer
by: Ge, Xiangfeng
Published: (2014)

Physical Exertion Immediately Prior to Placental Abruption: A Case-Crossover Study
by: Chahal, Harpreet S, et al.
Published: (2018)

The Acute Effects of Interval-Type Exercise on Glycemic Control in Type 2 Diabetes Subjects: Importance of Interval Length. A Controlled, Counterbalanced, Crossover Study.
by: Ida Jakobsen, et al.
Published: (2016-01-01)

The effect of aerobic exercise combined with metformin on ischemic cerebral infarction and its effect on the molecular level of SOD
by: Yang Sun, et al.
Published: (2020-06-01)

The effect of carbohydrate mouth rinse on performance, biochemical and psychophysiological variables during a cycling time trial: a crossover randomized trial
by: Amanda M. J. Ferreira, et al.
Published: (2018-05-01)

Perceived effort of funtional activities after a period of mechanical ventilation
by: R. Roos, et al.
Published: (2002-01-01)

Physiological and biochemical responses to diet and exercise
by: Noble, Rosemary Jane
Published: (2011)

Hemodynamic Changes After Static and Dynamic Exercises and Treadmill Stress Test; Different Patterns in Patients with Primary Benign Exertional Headache?
by: Ramin Kordi, et al.
Published: (2012-06-01)

Hemodynamic Changes After Static and Dynamic Exercises and Treadmill Stress Test; Different Patterns in Patients with Primary Benign Exertional Headache?
by: Mohsen Rostami, et al.
Published: (2012-06-01)

Metformin does not compromise energy status in human skeletal muscle at rest or during acute exercise: A randomised, crossover trial
by: Jonas M. Kristensen, et al.
Published: (2019-12-01)

Optimizing the Interaction of Exercise Volume and Metformin to Induce a Clinically Significant Reduction in Metabolic Syndrome Severity: A Randomised Trial
by: Joyce S. Ramos, et al.
Published: (2020-05-01)

Metformin Does Not Inhibit Exercise-Induced Lipolysis in Adipose Tissue in Young Healthy Lean Men
by: Eva Krauzová, et al.
Published: (2018-05-01)

Exercise, but Not Metformin Prevents Loss of Muscle Function Due to Doxorubicin in Mice Using an In Situ Method
by: Amy D. Mackay, et al.
Published: (2021-08-01)

Metformin to Augment Strength Training Effective Response in Seniors (MASTERS): study protocol for a randomized controlled trial
by: Doug E. Long, et al.
Published: (2017-04-01)

Effect of extremely weak pulsed magnetic field type Bemer 3000 on ratings of perceived exertion
by: D Gazurek, et al.
Published: (2008-06-01)

Combination of Metformin and Exercise in Management of Metabolic Abnormalities Observed in Type 2 Diabetes Mellitus
by: Jevtovic F
Published: (2021-09-01)

Exercise versus Metformin to Improve Pregnancy Outcomes among Overweight Pregnant Women: A Systematic Review and Network Meta-Analysis
by: Carlos Pascual-Morena, et al.
Published: (2021-08-01)

Blocking endogenous IL-6 impairs mobilization of free fatty acids during rest and exercise in lean and obese men
by: Beckey Trinh, et al.
Published: (2021-09-01)

Peak exercise capacity prediction from a submaximal exercise test in coronary artery disease patients
by: Arto J Hautala, et al.
Published: (2013-09-01)

Obesity as a noticeable cause of physical stress; A study on relationship of physical exertion and cardiovascular parameters
by: Ammara Farooq, et al.
Published: (2016-03-01)

Determination of ventilatory threshold based on rating of perceived exertion scale
by: Stojiljković Stanimir, et al.
Published: (2004-01-01)

Effects of Six Weeks of High-Intensity Functional Training on Physical Performance in Subjects with Different Training Volumes and Frequencies
by: Rômulo Vasconcelos Teixeira, et al.
Published: (2020-08-01)

ASSESSMENT OF SUBJECTIVE PERCEIVED EXERTION AT THE ANAEROBIC THRESHOLD WITH THE BORG CR-10 SCALE
by: Antonio R. Zamunér, et al.
Published: (2011-01-01)

Leukocyte, red blood cell and morphological adaptation to moderate physical training in rats undernourished in the neonatal period
by: Marcelo Tavares Viana, et al.
Published: (2012-01-01)

Effects of physical, virtual reality-based, and brain exercise on physical, cognition, and preference in older persons: a randomized controlled trial
by: Thwe Zar Chi Htut, et al.
Published: (2018-10-01)

Dynamics of chest wall volume regulation during constant work rate exercise in patients with chronic obstructive pulmonary disease
by: L.S. Takara, et al.
Published: (2012-12-01)

Effects of music and video on perceived exertion during high-intensity exercise
by: Enoch C. Chow, et al.
Published: (2017-03-01)

Decomposing Gender Disparity in Total Physical Activity among Iranian Adults
by: Ebrahim Rahimi, et al.
Published: (2017-10-01)

Cardiopulmonary exercise testing – Its application in cardiology and occupational medicine
by: Małgorzata Kurpesa, et al.
Published: (2014-10-01)

The Effects of a Korean Ginseng, GINST15, on Perceptual Effort, Psychomotor Performance, and Physical Performance in Men and Women
by: Lydia K. Caldwell, William H. DuPont, Matthew K. Beeler, Emily M. Post, Emily C. Barnhart, Vincent H. Hardesty, John P. Anders, Emily C. Borden, Jeff S. Volek, William J. Kraemer
Published: (2018-03-01)

The effects of prior oral creatine supplementation on performance and metabolism after 7 days of sprint cycle training
by: Bold, Antoinette
Published: (2018)

Back to basics with active lifestyles: exercise is more effective than metformin to reduce cardiovascular risk in older adults with type 2 diabetes
by: Liliana C. Baptista, et al.
Published: (2018-09-01)

Effects of the Visual Exercise Environments on Cognitive Directed Attention, Energy Expenditure and Perceived Exertion
by: Mike Rogerson, et al.
Published: (2015-06-01)

Resting Metabolic Rate Does Not Change in Response to Different Types of Training in Subjects with Type 2 Diabetes
by: Kristian Karstoft, et al.
Published: (2017-06-01)

Is Sickle Cell Trait as Benign as is Usually Assumed?
by: Flansburg, Carroll Nicole
Published: (2014)

Acute responses of blood pressure, heart rate and rating of perceived exertion in hypertensive patients
by: César Giovanni García Cardona, et al.
Published: (2007-06-01)

Drive in Sports: How Mental Fatigue Affects Endurance Performance
by: Lieke Schiphof-Godart, et al.
Published: (2018-08-01)

Cannot write session to /tmp/vufind_sessions/sess_vhh8e9itr5m6jn7ldf6jfv2t4n