Reduced radiation exposure for face transplant surgical planning computed tomography angiography.

To test the hypothesis that wide area detector face transplant surgical planning CT angiograms with simulated lower radiation dose and iterative reconstruction (AIDR3D) are comparable in image quality to those with standard tube current and filtered back projection (FBP) reconstruction.The sinograms...

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Main Authors: Kurt Schultz, Elizabeth George, Katherine M Mullen, Michael L Steigner, Dimitrios Mitsouras, Ericka M Bueno, Bohdan Pomahac, Frank J Rybicki, Kanako K Kumamaru
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3637203?pdf=render
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spelling doaj-69bbf109e7394fc6b3a9f253af03d5ef2020-11-25T00:40:52ZengPublic Library of Science (PLoS)PLoS ONE1932-62032013-01-0184e6307910.1371/journal.pone.0063079Reduced radiation exposure for face transplant surgical planning computed tomography angiography.Kurt SchultzElizabeth GeorgeKatherine M MullenMichael L SteignerDimitrios MitsourasEricka M BuenoBohdan PomahacFrank J RybickiKanako K KumamaruTo test the hypothesis that wide area detector face transplant surgical planning CT angiograms with simulated lower radiation dose and iterative reconstruction (AIDR3D) are comparable in image quality to those with standard tube current and filtered back projection (FBP) reconstruction.The sinograms from 320-detector row CT angiography of four clinical candidates for face transplantation were processed utilizing standard FBP, FBP with simulated 75, 62, and 50% tube current, and AIDR3D with corresponding dose reduction. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were measured at muscle, fat, artery, and vein. Image quality for each reconstruction strategy was assessed by two independent readers using a 4-point scale.Compared to FBP, the median SNR and CNR for AIDR3D images were higher at all sites for all 4 different tube currents. The AIDR3D with simulated 50% tube current achieved comparable SNR and CNR to FBP with standard dose (median muscle SNR: 5.77 vs. 6.23; fat SNR: 6.40 vs. 5.75; artery SNR: 43.8 vs. 45.0; vein SNR: 54.9 vs. 55.7; artery CNR: 38.1 vs. 38.6; vein CNR: 49.0 vs. 48.7; all p-values >0.19). The interobserver agreement in the image quality score was good (weighted κ = 0.7). The overall score and the scores for smaller arteries were significantly lower when FBP with 50% dose reduction was used. The AIDR3D reconstruction images with 4 different simulated doses achieved a mean score ranging from 3.68 to 3.82 that were comparable to the scores from images reconstructed using FBP with original dose (3.68-3.77).Simulated radiation dose reduction applied to clinical CT angiography for face transplant planning suggests that AIDR3D allows for a 50% reduction in radiation dose, as compared to FBP, while preserving image quality.http://europepmc.org/articles/PMC3637203?pdf=render
collection DOAJ
language English
format Article
sources DOAJ
author Kurt Schultz
Elizabeth George
Katherine M Mullen
Michael L Steigner
Dimitrios Mitsouras
Ericka M Bueno
Bohdan Pomahac
Frank J Rybicki
Kanako K Kumamaru
spellingShingle Kurt Schultz
Elizabeth George
Katherine M Mullen
Michael L Steigner
Dimitrios Mitsouras
Ericka M Bueno
Bohdan Pomahac
Frank J Rybicki
Kanako K Kumamaru
Reduced radiation exposure for face transplant surgical planning computed tomography angiography.
PLoS ONE
author_facet Kurt Schultz
Elizabeth George
Katherine M Mullen
Michael L Steigner
Dimitrios Mitsouras
Ericka M Bueno
Bohdan Pomahac
Frank J Rybicki
Kanako K Kumamaru
author_sort Kurt Schultz
title Reduced radiation exposure for face transplant surgical planning computed tomography angiography.
title_short Reduced radiation exposure for face transplant surgical planning computed tomography angiography.
title_full Reduced radiation exposure for face transplant surgical planning computed tomography angiography.
title_fullStr Reduced radiation exposure for face transplant surgical planning computed tomography angiography.
title_full_unstemmed Reduced radiation exposure for face transplant surgical planning computed tomography angiography.
title_sort reduced radiation exposure for face transplant surgical planning computed tomography angiography.
publisher Public Library of Science (PLoS)
series PLoS ONE
issn 1932-6203
publishDate 2013-01-01
description To test the hypothesis that wide area detector face transplant surgical planning CT angiograms with simulated lower radiation dose and iterative reconstruction (AIDR3D) are comparable in image quality to those with standard tube current and filtered back projection (FBP) reconstruction.The sinograms from 320-detector row CT angiography of four clinical candidates for face transplantation were processed utilizing standard FBP, FBP with simulated 75, 62, and 50% tube current, and AIDR3D with corresponding dose reduction. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were measured at muscle, fat, artery, and vein. Image quality for each reconstruction strategy was assessed by two independent readers using a 4-point scale.Compared to FBP, the median SNR and CNR for AIDR3D images were higher at all sites for all 4 different tube currents. The AIDR3D with simulated 50% tube current achieved comparable SNR and CNR to FBP with standard dose (median muscle SNR: 5.77 vs. 6.23; fat SNR: 6.40 vs. 5.75; artery SNR: 43.8 vs. 45.0; vein SNR: 54.9 vs. 55.7; artery CNR: 38.1 vs. 38.6; vein CNR: 49.0 vs. 48.7; all p-values >0.19). The interobserver agreement in the image quality score was good (weighted κ = 0.7). The overall score and the scores for smaller arteries were significantly lower when FBP with 50% dose reduction was used. The AIDR3D reconstruction images with 4 different simulated doses achieved a mean score ranging from 3.68 to 3.82 that were comparable to the scores from images reconstructed using FBP with original dose (3.68-3.77).Simulated radiation dose reduction applied to clinical CT angiography for face transplant planning suggests that AIDR3D allows for a 50% reduction in radiation dose, as compared to FBP, while preserving image quality.
url http://europepmc.org/articles/PMC3637203?pdf=render
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