HIV-1 replication in cell lines harboring INI1/hSNF5 mutations

<p>Abstract</p> <p>Background</p> <p>INI1/hSNF5 is a cellular protein that directly interacts with HIV-1 integrase (IN). It is specifically incorporated into HIV-1 virions. A dominant negative mutant derived from INI1 inhibits HIV-1 replication. Recent studies indicate...

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Bibliographic Details
Main Authors: Wu Xuhong, Yung Eric, Sorin Masha, Kalpana Ganjam V
Format: Article
Language:English
Published: BMC 2006-08-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/3/1/56