Intracellular calcium release modulates polycystin-2 trafficking

Intracellular calcium release modulates polycystin-2 trafficking

<p>Abstract</p> <p>Background</p> <p>Polycystin-2 (PC2), encoded by the gene that is mutated in autosomal dominant polycystic kidney disease (ADPKD), functions as a calcium (Ca<sup>2+</sup>) permeable ion channel. Considerable controversy remains regarding t...

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Bibliographic Details
Main Authors: Miyakawa Ayako, Ibarra Cristián, Malmersjö Seth, Aperia Anita, Wiklund Peter, Uhlén Per
Format: Article
Language:English
Published: BMC 2013-02-01
Series:BMC Nephrology
Subjects:
Polycystin-2
Protein trafficking
Calcium signaling
Kidney cells
Autosomal dominant polycystic kidney disease
Online Access:http://www.biomedcentral.com/1471-2369/14/34

Internet

http://www.biomedcentral.com/1471-2369/14/34

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