Brucella abortus Induces the Premature Death of Human Neutrophils through the Action of Its Lipopolysaccharide.

Most bacterial infections induce the activation of polymorphonuclear neutrophils (PMNs), enhance their microbicidal function, and promote the survival of these leukocytes for protracted periods of time. Brucella abortus is a stealthy pathogen that evades innate immunity, barely activates PMNs, and r...

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Main Authors: Elías Barquero-Calvo, Ricardo Mora-Cartín, Vilma Arce-Gorvel, Juana L de Diego, Carlos Chacón-Díaz, Esteban Chaves-Olarte, Caterina Guzmán-Verri, Andre G Buret, Jean-Pierre Gorvel, Edgardo Moreno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4422582?pdf=render

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