Protective Effect of <i>Vitis labrusca</i> Leaves Extract on Cardiovascular Dysfunction through HMGB1-TLR4-NFκB Signaling in Spontaneously Hypertensive Rats

Protective Effect of <i>Vitis labrusca</i> Leaves Extract on Cardiovascular Dysfunction through HMGB1-TLR4-NFκB Signaling in Spontaneously Hypertensive Rats

The <i>Vitis labrusca</i> is a grapevine that has antioxidant, neuroprotective, hepatoprotective, and anticarcinogenic activity. However, the effect of <i>Vitis labrusca</i> leaves on the cardiovascular system is yet to be ascertained. The present study was designed to invest...

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Bibliographic Details
Main Authors: Hye Yoom Kim, Mi Hyeon Hong, Jung Joo Yoon, Dae Sung Kim, Se Won Na, Youn Jae Jang, Yun Jung Lee, Dae Gill Kang, Ho Sub Lee
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Nutrients
Subjects:
<i>Vitis labrusca</i> leaves (HP1)
hypertension
cardiovascular remodeling
HMGB1-TLR4-NFκB signaling
Online Access:https://www.mdpi.com/2072-6643/12/10/3096

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