Endothelial cell clonal expansion in the development of cerebral cavernous malformations
Cerebral cavernous malformation is a vascular disease characterized by capillary-venous cavernomas in the central nervous system. Here the authors show that cavernomas display benign tumor characteristics and originate from the clonal expansion of mutated endothelial progenitors which can attract su...
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Bibliographic Details
| Main Authors: |
Matteo Malinverno,
Claudio Maderna,
Abdallah Abu Taha,
Monica Corada,
Fabrizio Orsenigo,
Mariaelena Valentino,
Federica Pisati,
Carmela Fusco,
Paolo Graziano,
Monica Giannotta,
Qing Cissy Yu,
Yi Arial Zeng,
Maria Grazia Lampugnani,
Peetra U. Magnusson,
Elisabetta Dejana |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2019-06-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-019-10707-x
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