Gene Expression Analysis of Mevalonate Kinase Deficiency Affected Children Identifies Molecular Signatures Related to Hematopoiesis

Gene Expression Analysis of Mevalonate Kinase Deficiency Affected Children Identifies Molecular Signatures Related to Hematopoiesis

Mevalonate kinase deficiency (MKD) is a rare autoinflammatory genetic disorder characterized by recurrent fever attacks and systemic inflammation with potentially severe complications. Although it is recognized that the lack of protein prenylation consequent to mevalonate pathway blockade drives IL1...

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Bibliographic Details
Main Authors: Simona Pisanti, Marianna Citro, Mario Abate, Mariella Caputo, Rosanna Martinelli
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Environmental Research and Public Health
Subjects:
mevalonate kinase deficiency
anemia
hematopoiesis
stress erythropoiesis
Online Access:https://www.mdpi.com/1660-4601/18/3/1170

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