Prognostic value of blood-based fibrosis biomarkers in patients with metastatic colorectal cancer receiving chemotherapy and bevacizumab

Prognostic value of blood-based fibrosis biomarkers in patients with metastatic colorectal cancer receiving chemotherapy and bevacizumab

Abstract A desmoplastic colorectal cancer stroma, characterized by excess turnover of the cancer-associated fibroblast derived collagens type III and VI, can lead to reduced drug-uptake and poor treatment response. We investigated the association between biomarkers of collagen type III and VI and ov...

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Bibliographic Details
Main Authors: Neel I. Nissen, Stephanie Kehlet, Mogens K. Boisen, Maria Liljefors, Christina Jensen, Astrid Z. Johansen, Julia S. Johansen, Janine T. Erler, Morten Karsdal, Joachim H. Mortensen, Anette Høye, Nicholas Willumsen
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79608-0

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https://doi.org/10.1038/s41598-020-79608-0

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