A genetic analysis of the functional interactions within Mycobacterium tuberculosis single-stranded DNA binding protein.

A genetic analysis of the functional interactions within Mycobacterium tuberculosis single-stranded DNA binding protein.

Single-stranded DNA binding proteins (SSBs) are vital in all organisms. SSBs of Escherichia coli (EcoSSB) and Mycobacterium tuberculosis (MtuSSB) are homotetrameric. The N-terminal domains (NTD) of these SSBs (responsible for their tetramerization and DNA binding) are structurally well defined. Howe...

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Bibliographic Details
Main Authors: Kervin Rex, Sanjay Kumar Bharti, Shivjee Sah, Umesh Varshney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3983218?pdf=render

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