Transepithelial transport of P-glycoprotein substrate by the Malpighian tubules of the desert locust.

Extrusion of xenobiotics is essential for allowing animals to remove toxic substances present in their diet or generated as a biproduct of their metabolism. By transporting a wide range of potentially noxious substrates, active transporters of the ABC transporter family play an important role in xen...

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Bibliographic Details
Main Authors: Marta Rossi, Davide De Battisti, Jeremy Edward Niven
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0223569